Tech-method Course:
Proteomics

Date
3-4-5 March 2026

Organizers
Angela Bachi (IFOM) & Tiziana Bonaldi (IEO)

Location
IEO Campus, Via Adamello 16 - Milan
About the Course
This course introduces the fundamentals of proteomics while fostering a critical understanding of its most advanced biomedical applications. Students will learn core analytical principles, experimental design, and data interpretation, developing the ability to evaluate emerging proteomic technologies. Emphasis is placed on appreciating both the immense potential and the current challenges of proteomics in biomedical research.
Lessons Location: Coral Room
9:15 – 9:30
Course introduction
A. Bachi/T. Bonaldi
9:30 – 11:00
Introduction to proteomics MS
A. Bachi – IFOM
11:15 – 12:45
Quantitative Proteomics/Expression proteomics with reference to data analysis
A. Cuomo – IEO
14:00 – 15:30
Challenges in PTMs analysis
T. Bonaldi – IEO
15:45 – 17:00
Interaction proteomics & proximity proteomics
T. Bonaldi – IEO
Lessons Location: Coral Room
9:15 – 10:30
Single cell & Spatial Proteomics (super-sensitive sample prep + MS and MS and Ab strengths/caveats)
A. Bachi – IFOM
10:45 – 12:30
Proteomics in clinical research & Drug Discovery, with some examples on HT & automation
R. Noberini – IEO
14:00 – 15:00
The impact of AI in proteomics
A. Vai – IEO
15:15 – 17:00
Mastering the Experimental System: from wet lab preparation to data interpretation
M. Murgia – University of Padua & Max Planck Institute of Biochemistry, Martinsried
Lessons Location: Coral Room
9:15 – 12:15
Data Analysis Tutorial #1
A. Cuomo – IEO
13:30 – 14:30
Spatial Proteomics & Data Analysis
D. Schapiro – IFOM & University of Heidelberg
14:45 – 17:30
Data Analysis, Statistics and Functional Annotation Tutorial #2
A. Cuomo – IEO + Matafora IFOM
17:30
Closing Remarks
A. Bachi/T. Bonaldi